High Prenatal Exposure to Bisphenol A Reduces Anogenital Distance in Healthy Male Newborns
نویسندگان
چکیده
منابع مشابه
High Prenatal Exposure to Bisphenol A Reduces Anogenital Distance in Healthy Male Newborns
OBJECTIVE To estimate the relationship between cord blood bisphenol A (BPA) levels and anogenital measurements in healthy newborns. METHODS Pregnancy and birth history, together with body mass and length data, anogenital measurements, penile measurements and cord blood samples were obtained from healthy newborns. Cord blood concentration of BPA was analyzed by sandwich enzyme-linked immunosor...
متن کاملPrenatal exposure to antifungal medication may change anogenital distance in male offspring: a preliminary study
BACKGROUND Vaginal candidiasis is frequent among pregnant women and it is treated with anti-fungal medication (conazoles). Conazoles have anti-androgenic properties and prenatal exposure in rodents is associated with a shorter (less masculine) anogenital distance (AGD) in male offspring. To our knowledge this has never been studied in humans. METHOD In the Odense Child Cohort pregnant women r...
متن کاملAnogenital Distance in Turkish Newborns
OBJECTIVE Anogenital distances are considered to be a sensitive indicator of external genitalia exposure to factors such as anti-androgens, and/or endocrine distruptors during the prenatal period. Exposure to such factors can lead to changes in the anogenital measurements (AGM) of newborn infants. These measurements can be used to predict masculinization of the external genitalia in healthy new...
متن کاملAnogenital Distance in Turkish Newborns
We have measured anogenital distance (AGD) in 300 newborns delivered in Zubeyde Hanim Maternity Hospital in 2007. As in the study by Ozkan et al (1), we also used a sliding caliper for the measurements; however, in the manuscript by Ozkan et al (1), it was mentioned as tape, which needs correction. The results of both Dr Ozkan’s study and ours seem similar. We could not give the results of meas...
متن کاملFirst trimester phthalate exposure and anogenital distance in newborns.
STUDY QUESTION Is first trimester phthalate exposure associated with anogenital distance (AGD), a biomarker of prenatal androgen exposure, in newborns? SUMMARY ANSWER Concentrations of diethylhexyl phthalate (DEHP) metabolites in first trimester maternal urine samples are inversely associated with AGD in male, but not female, newborns. WHAT IS KNOWN ALREADY AGD is a sexually dimorphic measu...
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ژورنال
عنوان ژورنال: Journal of Clinical Research in Pediatric Endocrinology
سال: 2018
ISSN: 1308-5727
DOI: 10.4274/jcrpe.4817